OBJECTIVE: To investigate the relationship between changes in high density lipoprotein cholesterol(HDL-C) levels after statin treatment and the risk for coronary heart disease (CHD)-related events in the secondary CHD prevention GREek Atorvastatin and Coronary heart disease Evaluation (GREACE) Study. See risks and benefits of LIPITOR® (atorvastatin calcium) and learn how LIPITOR can help manage cholesterol as well as reduce risk of heart attack and stroke. Common risk factors include: Family history of heart disease; High blood pressure; Age; Low HDL (“good”) cholesterol; Smoking.
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However, recent investigations suggest that differences may exist between simvastatin and atorvastatin in their ability to raise HDL levels. Simvastatin has clearly better HDL-raising capacity compared with a dose of atorvastatin, with broadly similar LDL and triglyceride lowering effects[30,31,32,33,34,35]. In addition, the. Lipitor goes generic in , erasing $8 billion in U.S. sales for Pfizer. Which underscores why the drug industry is on an urgent hunt for a savior. For a few years it thought it had one: good cholesterol, also known as high-density lipoprotein. The mysterious HDL is thought to unclog arteries gunked up by.
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